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Article

A two-stage approach to genetic risk assessment in primary care.

Breast cancer research and treatment - 1 Jan 2016

Biswas Swati, Atienza Philamer, Chipman Jonathan, Blackford Amanda L, Arun Banu, Hughes Kevin, Parmigiani Giovanni

Abstract excerpt

Genetic risk prediction models such as BRCAPRO are used routinely in genetic counseling for identification of potential BRCA1 and BRCA2 mutation carriers. They require extensive information on the counselee and her family history, and thus are not practical for primary care. To address this gap, we develop and test a two-stage approach to genetic risk assessment by balancing the tradeoff between the amount of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26786860
DOI: 10.1007/s10549-016-3686-2
PMCID: PMC4742331

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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