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Article

Optimal selection of individuals for BRCA mutation testing: a comparison of available methods.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Feb 2006

James Paul A, Doherty Rebecca, Harris Marion, Mukesh Bickol N, Milner Alvin, Young Mary-Anne, Scott Clare

Abstract excerpt

PURPOSE: Several methods have been described that estimate the likelihood that a family history of cancer is a result of a mutation in the BRCA1 or BRCA2 genes. We examined the performance of six different methods with the aim of identifying an optimal strategy for selecting individuals for mutat...

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Source

Identifiers

PMID: 16446345
DOI: 10.1200/JCO.2005.01.9737

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-16446345-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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