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Article

Comparison of Practice Guidelines, BRCAPRO, and Genetic Counselor Estimates to Identify Germline BRCA1 and BRCA2 Mutations in Pancreatic Cancer.

Journal of genetic counseling - 1 Aug 2018

Grant Robert C, Holter Spring, Borgida Ayelet, Dhani Neesha C, Hedley David W, Knox Jennifer J, Akbari Mohammad R, Zogopoulos George, Gallinger Steven

Abstract excerpt

Germline BRCA1 and BRCA2 (BRCA) mutation carriers with pancreatic ductal adenocarcinoma (PDAC) may benefit from precision therapies and their relatives should undergo tailored cancer prevention. In this study, we compared strategies to identify BRCA carriers with PDAC. Incident cases of PDAC were prospectively recruited for BRCA sequencing. Probands were evaluated using the National Comprehensive Cancer Network...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29441441
DOI: 10.1007/s10897-018-0212-1

Genes

BRCA1
BRCA2

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