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Article

Validation of the pedigree assessment tool (PAT) in families with BRCA1 and BRCA2 mutations.

Annals of surgical oncology - 1 Jan 2010

Teller P, Hoskins K F, Zwaagstra A, Stanislaw C, Iyengar R, Green V L, Gabram S G A

Abstract excerpt

BACKGROUND: The lifetime risk of breast cancer (BC) in patients with hereditary breast cancer syndromes is as high as 80%. The Pedigree Assessment Tool (PAT) is a scoring system to aid in identifying these patients. This validation study compares the PAT to BRCA gene mutation probability models in predicting suitability for genetic referral. METHODS: Retrospective review identified subjects undergoing genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19763692
DOI: 10.1245/s10434-009-0697-9

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Validation of the pedigree assessment tool (PAT) in families with BRCA1 and BRCA2 mutations.PMID 19763692Read ↗

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