Article
Quantitative prediction of NF-kappa B DNA-protein interactions.
Proceedings of the National Academy of Sciences of the United States of America - 11 Jun 2002
Udalova Irina A, Mott Richard, Field Dawn, Kwiatkowski Dominic
Abstract excerpt
We describe a general method based on principal coordinates analysis to predict the effects of single-nucleotide polymorphisms within regulatory sequences on DNA-protein interactions. We use binding data for the transcription factor NF-kappaB as a test system. The method incorporates the effects...
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