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Article

Single-nucleotide mutation matrix: a new model for predicting the NF-κB DNA binding sites.

PloS one - 1 Jan 2014

Du Wenxin, Gao Jing, Wang Tingting, Wang Jinke

Abstract excerpt

In this study, we established a single nucleotide mutation matrix (SNMM) model based on the relative binding affinities of NF-κB p50 homodimer to a wild-type binding site (GGGACTTTCC) and its all single-nucleotide mutants detected with the double-stranded DNA microarray. We evaluated this model by scoring different groups of 10-bp DNA sequences with this model and analyzing the correlations between the scores and...

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Identifiers

PMID: 24992458
DOI: 10.1371/journal.pone.0101490
PMCID: PMC4081663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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