Article
BayesPI-BAR: a new biophysical model for characterization of regulatory sequence variations.
Nucleic acids research - 2 Dec 2015
Wang Junbai, Batmanov Kirill
Abstract excerpt
Sequence variations in regulatory DNA regions are known to cause functionally important consequences for gene expression. DNA sequence variations may have an essential role in determining phenotypes and may be linked to disease; however, their identification through analysis of massive genome-wide sequencing data is a great challenge. In this work, a new computational pipeline, a Bayesian method for protein-DNA...
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