Article
PiDNA: Predicting protein-DNA interactions with structural models.
Nucleic acids research - 1 Jul 2013
Lin Chih-Kang, Chen Chien-Yu
Abstract excerpt
Predicting binding sites of a transcription factor in the genome is an important, but challenging, issue in studying gene regulation. In the past decade, a large number of protein-DNA co-crystallized structures available in the Protein Data Bank have facilitated the understanding of interacting mechanisms between transcription factors and their binding sites. Recent studies have shown that both physics-based and...
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