Altered levels of Gq activity modulate axonal pathfinding in Drosophila.

Abstract excerpt

A majority of neurons that form the ventral nerve cord send out long axons that cross the midline through anterior or posterior commissures. A smaller fraction extend longitudinally and never cross the midline. The decision to cross the midline is governed by a balance of attractive and repulsive signals. We have explored the role of a G-protein, Galphaq, in altering this balance in Drosophila. A splice variant...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Axons
• Share to Central Nervous System
• Share to Embryo, Nonmammalian