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Article

Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype.

The Journal of biological chemistry - 16 Aug 2002

Rennefahrt Ulrike E E, Illert Bertram, Kerkhoff Eugen, Troppmair Jakob, Rapp Ulf R

Abstract excerpt

The c-Jun N-terminal kinases (JNKs) (also known as stress-activated protein kinases or SAPKs), members of the mitogen-activated protein kinase (MAPK) family, regulate gene expression in response to a variety of physiological and unphysiological stimuli. Gene knockout experiments and the use of dominant interfering mutants have pointed to a role for JNKs in the processes of cell differentiation and survival as...

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Identifiers

PMID: 12039958
DOI: 10.1074/jbc.M203010200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype.PMID 12039958Read ↗

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