Article
Polymorphism at codon 72 of p53, human papillomavirus, and cervical cancer in South India.
Journal of cancer research and clinical oncology - 1 Nov 2002
Pillai M Radhakrishna, Sreevidya S, Pollock Brad H, Jayaprakash P G, Herman Brian
Abstract excerpt
PURPOSE: It has been suggested that host genetic factors play a role in human papillomavirus (HPV)-associated tumorigenesis, although the issue continues to be a focus of much debate. Previous studies have reported that a common polymorphism of the wild type p53 gene at codon 72 of exon 4 (Arg/Arg) is associated with a sevenfold increased risk of HPV-associated cancer compared to Arg/Pro and Pro/Pro...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.