Article
p53 at codon 72 polymorphism, human papillomavirus infection and cervical lesions: a cross-sectional study from northeastern Italy.
European journal of obstetrics, gynecology, and reproductive biology - 15 Jun 2004
Comar Manola, Molin Gianna Dal, Guaschino Secondo, Campello Cesare
Abstract excerpt
OBJECTIVE: To test the hypothesis that p53 homozygous Arg/Arg genotype at codon 72 is a significant risk factor for the development of HPV induced cervical cancer. STUDY DESIGN: A cross-sectional survey on p53 allelotypes distribution in women with different grade of cervical lesions and with or without HPV infection, in comparison to the distribution on a control group of women cytologically normal and HPV...
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