Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination.

Gene - 20 Feb 2002

Ashley Carolyn, Pastushok Landon, McKenna Sean, Ellison Michael J, Xiao Wei

Abstract excerpt

The E2 enzyme, Ubc13, and the E2 enzyme variants, Uevs, form stable, high affinity complexes for the assembly of Lys63-linked ubiquitin chains. This process is involved in error-free DNA postreplication repair, the activation of kinases in the NF-kappaB signaling pathway and possibly other cellular processes. To further investigate the roles played by Ubc13 in a whole animal model, we report here the molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Replication
Share to Genetic Complementation Test
Share to Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lysine

Share to Trans-Activators

Share to Two-Hybrid System Techniques

Share to Ubiquitin

Share to Ubiquitin-Conjugating Enzymes

Source

Identifiers

PMID: 12039045
DOI: 10.1016/s0378-1119(02)00409-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination.PMID 12039045Read ↗

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling.Semantic proximity Read ↗

Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality.Semantic proximity Read ↗

Molecular cloning and functional characterization of UBC13 and MMS2 from Candida albicans.Semantic proximity Read ↗

The mouse and human genes encoding the recognition component of the N-end rule pathwaySemantic proximity Read ↗

Drosophila bendless catalyzes K63-linked polyubiquitination and is involved in the response to DNA damage.Semantic proximity Read ↗

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.Semantic proximity Read ↗

UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of p53 localization and activity by Ubc13.Semantic proximity Read ↗

The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis.Semantic proximity Read ↗

Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9.Semantic proximity Read ↗

Deficiency of murine UFM1-specific E3 ligase causes microcephaly and inflammationSemantic proximity Read ↗

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage responseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.