Article
Seven single nucleotide substitutions in human Fc(gamma) receptor IIB gene.
Tissue antigens - 1 Nov 2001
Yasuda K, Sugita N, Yamamoto K, Kobayashi T, Yoshie H
Abstract excerpt
Variation screening for the immunoglobulin G Fc receptor IIB (Fc(gamma)RIIB) gene was performed with the genomic DNA from 100 healthy Japanese subjects. We identified 3 non-synonymous and 2 synonymous substitutions and 2 single-nucleotide polymorphisms in an intron region. These substitutions were found to be located in the ligand-binding domain and the intron, which might alter the function of Fc(gamma)RIIb.
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