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Article

Recessive transmission of a multiple endocrine neoplasia syndrome in the rat.

Cancer research - 1 Jun 2002

Fritz Andreas, Walch Axel, Piotrowska Kamilla, Rosemann Michael, Schäffer Ekkehard, Weber Karin, Timper Andreas, Wildner Gerhild, Graw Jochen, Höfler Heinz, Atkinson Michael J

Abstract excerpt

We describe a novel hereditary cancer syndrome in the rat that is transmitted by a recessive gene mutation. Animals exhibiting the mutant phenotype develop multiple neuroendocrine malignancies within the first year of life. The endocrine neoplasia is characterized by bilateral adrenal pheochromocytoma, multiple extra-adrenal pheochromocytoma, bilateral medullary thyroid cell neoplasia, bilateral parathyroid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-ret

Share to Rats, Sprague-Dawley

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Share to Receptor Protein-Tyrosine Kinases

Source

Identifiers

PMID: 12036912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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