Article
Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia.
Carcinogenesis - 1 Mar 2008
Matoso Andres, Zhou Zongxiang, Hayama Ryo, Flesken-Nikitin Andrea, Nikitin Alexander Yu
Abstract excerpt
Inactivation of multiple endocrine neoplasia (MEN) type 1 gene (Men1) results in development of multiple endocrine tumors in Men1(+/-) mice and in humans. Intriguingly, loss of the wild-type retinoblastoma 1 (Rb) gene also leads to MEN-like phenotype in Rb(+/-) mice. To evaluate potential genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
