Article
Animal models of multiple endocrine neoplasia.
Molecular and cellular endocrinology - 5 Feb 2016
Wiedemann Tobias, Pellegata Natalia S
Abstract excerpt
Multiple endocrine neoplasia (MEN) syndromes are autosomal dominant diseases with high penetrance characterized by proliferative lesions (usually hyperplasia or adenoma) arising in at least two endocrine tissues. Four different MEN syndromes have been so far identified: MEN type 1 (MEN1), MEN2A (also referred to as MEN2), MEN2B (or MEN3) and MEN4, which have slightly varying tumor spectra and are caused by...
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