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Article

The Toll and Imd pathways are the major regulators of the immune response in Drosophila.

The EMBO journal - 3 Jun 2002

De Gregorio Ennio, Spellman Paul T, Tzou Phoebe, Rubin Gerald M, Lemaitre Bruno

Abstract excerpt

Microarray studies have shown recently that microbial infection leads to extensive changes in the Drosophila gene expression programme. However, little is known about the control of most of the fly immune-responsive genes, except for the antimicrobial peptide (AMP)-encoding genes, which are regulated by the Toll and Imd pathways. Here, we used oligonucleotide microarrays to monitor the effect of mutations...

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Identifiers

PMID: 12032070
DOI: 10.1093/emboj/21.11.2568
PMCID: PMC126042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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