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Article

In vivo RNA interference analysis reveals an unexpected role for GNBP1 in the defense against Gram-positive bacterial infection in Drosophila adults.

The Journal of biological chemistry - 26 Mar 2004

Pili-Floury Sebastien, Leulier François, Takahashi Kuniaki, Saigo Kaoru, Samain Emmanuel, Ueda Ryu, Lemaitre Bruno

Abstract excerpt

The Drosophila immune system discriminates between different classes of infectious microbes and responds with pathogen-specific defense reactions via the selective activation of the Toll and the immune deficiency (Imd) signaling pathways. The Toll pathway mediates most defenses against Gram-positive bacteria and fungi, whereas the Imd pathway is required to resist Gram-negative bacterial infection. Microbial...

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Identifiers

PMID: 14722090
DOI: 10.1074/jbc.M313324200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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