Article
A rapid, membrane-dependent pathway directs furrow formation through RalA in the early Drosophila embryo.
Development (Cambridge, England) - 1 Jul 2015
Holly Ryan M, Mavor Lauren M, Zuo Zhongyuan, Blankenship J Todd
Abstract excerpt
Plasma membrane furrow formation is crucial in cell division and cytokinesis. Furrow formation in early syncytial Drosophila embryos is exceptionally rapid, with furrows forming in as little as 3.75 min. Here, we use 4D imaging to identify furrow formation, stabilization, and regression periods, and identify a rapid, membrane-dependent pathway that is essential for plasma membrane furrow formation in vivo. Myosin...
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