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Article

4G/5G promoter polymorphism of plasminogen activator inhibitor-1, lipid profiles, and ischemic stroke.

The Journal of laboratory and clinical medicine - 1 Aug 2003

Chen Chih-Hung, Eng Hock-Liew, Chang Chih-Jen, Tsai Tzu-Tung, Lai Ming-Liang, Chen Hsiao-Yen, Liu Chien-Ju, Lin Tsun-Mei

Abstract excerpt

The 4G allele of common 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene is associated with increased PAI-1 transcription and has been proposed as a candidate genetic risk factor for thrombotic diseases. We investigated the relationship between this polymorphism and lipid profiles and stroke risk. One hundred patients with ischemic stroke and 150 age- and sex-matched...

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Identifiers

PMID: 12960956
DOI: 10.1016/S0022-2143(03)00063-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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