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Article

Yeast Vps55p, a functional homolog of human obesity receptor gene-related protein, is involved in late endosome to vacuole trafficking.

Molecular biology of the cell - 1 May 2002

Belgareh-Touzé Naïma, Avaro Sandrine, Rouillé Yves, Hoflack Bernard, Haguenauer-Tsapis Rosine

Abstract excerpt

The Saccharomyces cerevisiae VPS55 (YJR044c) gene encodes a small protein of 140 amino acids with four potential transmembrane domains. VPS55 belongs to a family of genes of unknown function, including the human gene encoding the obesity receptor gene-related protein (OB-RGRP). Yeast cells with a disrupted VPS55 present normal vacuolar morphology, but exhibit an abnormal secretion of the Golgi form of the soluble...

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Identifiers

PMID: 12006663
DOI: 10.1091/mbc.01-12-0597
PMCID: PMC111137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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