Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs.

The Journal of biological chemistry - 19 Jul 2002

Stahelin Robert V, Long Fei, Diraviyam Karthikeyan, Bruzik Karol S, Murray Diana, Cho Wonhwa

Abstract excerpt

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. To elucidate the mechanism by which the FYVE domain interacts with PtdIns(3)P-containing membranes, we measured the membrane binding of the FYVE domains of yeast Vps27p and Drosophila hepatocyte growth factor-regulated tyrosine kinase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microtubule-Associated Proteins

Share to Phosphatidylinositol Phosphates

Share to Phosphoproteins

Share to Static Electricity

Share to Vesicular Transport Proteins

Share to Zinc Fingers

Source

Identifiers

PMID: 12006563
DOI: 10.1074/jbc.M201106200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs.PMID 12006563Read ↗

Structural basis for endosomal targeting by FYVE domains.Semantic proximity Read ↗

Membrane insertion of the FYVE domain is modulated by pH.Semantic proximity Read ↗

The molecular basis of the differential subcellular localization of FYVE domains.Semantic proximity Read ↗

Phosphatidylinositol 3-phosphate recognition by the FYVE domain.Semantic proximity Read ↗

Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox.Semantic proximity Read ↗

Phosphoinositides differentially regulate protrudin localization through the FYVE domain.Semantic proximity Read ↗

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells.Semantic proximity Read ↗

Traffic to the malaria parasite food vacuole: a novel pathway involving a phosphatidylinositol 3-phosphate-binding protein.Semantic proximity Read ↗

Mechanistic insights into the phosphatidylinositol binding properties of the pleckstrin homology domain of lamellipodin.Semantic proximity Read ↗

Phosphatidylserine binding is essential for plasma membrane recruitment and signaling function of 3-phosphoinositide-dependent kinase-1.Semantic proximity Read ↗

Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity.Semantic proximity Read ↗

FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.