Article
Traffic to the malaria parasite food vacuole: a novel pathway involving a phosphatidylinositol 3-phosphate-binding protein.
The Journal of biological chemistry - 13 Apr 2007
McIntosh Michael T, Vaid Ankush, Hosgood H Dean, Vijay Justin, Bhattacharya Anindita, Sahani Mayurbhai H, Baevova Pavlina, Joiner Keith A, Sharma Pushkar
Abstract excerpt
Phosphatidylinositol 3-phosphate (PI3P) is a key ligand for recruitment of endosomal regulatory proteins in higher eukaryotes. Subsets of these endosomal proteins possess a highly selective PI3P binding zinc finger motif belonging to the FYVE domain family. We have identified a single FYVE domain...
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