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Article

Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox.

The Journal of biological chemistry - 18 Apr 2003

Stahelin Robert V, Burian Aura, Bruzik Karol S, Murray Diana, Cho Wonhwa

Abstract excerpt

Phox (PX) domains are phosphoinositide (PI)-binding domains with broad PI specificity. Two cytosolic components of NADPH oxidase, p40(phox) and p47(phox), contain PX domains. The PX domain of p40(phox) specifically binds phosphatidylinositol 3-phosphate, whereas the PX domain of p47(phox) has two lipid binding sites, one specific for phosphatidylinositol 3,4-bisphosphate and the other with affinity for...

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Identifiers

PMID: 12556460
DOI: 10.1074/jbc.M212579200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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