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Article

KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size.

The American journal of pathology - 1 May 2002

Corless Christopher L, McGreevey Laura, Haley Andrea, Town Ajia, Heinrich Michael C

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms of the gut wall that express the receptor tyrosine kinase KIT. Somatic mutations that result in constitutive activation of KIT kinase have been identified in a number of studies of GISTs, although the reported frequency of these mutations has varied over a wide range (20 to 92%). Several reports have suggested that KIT gene mutations are more...

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Identifiers

PMID: 12000708
DOI: 10.1016/S0002-9440(10)61103-0
PMCID: PMC1850861

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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