Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases.

doi:10.1038/modpathol.2008.2

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Article

Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2008

Lasota Jerzy, Corless Christopher L, Heinrich Michael C, Debiec-Rychter Maria, Sciot Raf, Wardelmann Eva, Merkelbach-Bruse Sabine, Schildhaus Hans-Ulrich, Steigen Sonja E, Stachura Jerzy, Wozniak Agnieszka, Antonescu Cristina, Daum Ondrej, Martin Javier, Del Muro Javier Garcia, Miettinen Markku

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms driven by oncogenic, mutational activation of KIT or platelet-derived growth factor receptor alpha (PDGFRA). GIST-specific KIT or PDGFRA mutations have been linked to tumor location, tumor cell morphology and clinical behavior. The purpose of this study was to evaluate the clinicopathologic profile of GISTs that have KIT exon 13 or exon 17...

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Identifiers

PMID: 18246046
DOI: 10.1038/modpathol.2008.2

Genes

KIT
PDGFRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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