Article
Clinical utility of a genetic susceptibility test for severe chronic periodontitis: a critical evaluation.
Journal of the American Dental Association (1939) - 1 Apr 2002
Greenstein Gary, Hart Thomas C
Abstract excerpt
BACKGROUND: A genetic susceptibility test for severe chronic periodontitis is now commercially available. It detects the simultaneous presence of a specific form of two interleukin genes--allele 2 at the IL1A+4845 and IL1B+3954 loci. Patients are referred to as being "genotype-positive" if both of these alleles are present. A fundamental premise of the test is that a combination of these alleles is responsible...
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