Article
Genotype and clinical management of periodontitis.
Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) - 1 Jan 2001
Newman M
Abstract excerpt
An increased level of interleukin-1 (IL-1) is a risk factor to adult periodontitis. The clinical significance of the initial finding that some people may have a genetic predisposition causing them to produce larger amounts of IL-1 in response to dental plaque has been clarified by numerous studies. While it appears that genotype-positive patients are at increased risk of severe periodontitis, genotype-negative...
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