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Article

Genetic predisposition to persistent apical periodontitis.

Journal of endodontics - 1 Apr 2011

Morsani Jussara M, Aminoshariae Anita, Han Yiping Weng, Montagnese Thomas A, Mickel Andre

Abstract excerpt

INTRODUCTION: The proinflammatory cytokine interleukin (IL)-1 is a key regulator of host responses to microbial infection and a major modulator of extracellular matrix catabolism and bone resorption. Allele2 of IL-1β is associated with a four-fold increase in IL-1β production. The aim of this case-control study was to evaluate the gene polymorphism of IL-1β in the pathogenesis of endodontic failure. We...

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Source

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Identifiers

PMID: 21419289
DOI: 10.1016/j.joen.2011.01.009
PMCID: PMC3845962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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