Article
Breast cancer in women at high risk: the role of rapid genetic testing for BRCA1 and -2 mutations and the consequences for treatment strategies.
Breast (Edinburgh, Scotland) - 1 Oct 2013
Francken Anne Brecht, Schouten Philip C, Bleiker Eveline M A, Linn Sabine C, Rutgers Emiel J Th
Abstract excerpt
Specific clinical questions rise when patients, who are diagnosed with breast cancer, are at risk of carrying a mutation in BRCA1 and -2 gene due to a strong family history or young age at diagnosis. These questions concern topics such as 1. Timing of genetic counseling and testing, 2. Choices to be made for BRCA1 or -2 mutation carriers in local treatment, contralateral treatment, (neo)adjuvant systemic therapy,...
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