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Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Oct 2011

Liamarkopoulos Emmanouil, Gazouli Maria, Aravantinos Gerasimos, Tzanakis Nikolaos, Theodoropoulos George, Rizos Spyros, Nikiteas Nikolaos

Abstract excerpt

BACKGROUND: Caspase-8 (CASP8) and caspase-9 (CASP9) play crucial roles in regulating apoptosis, and their functional polymorphisms may alter cancer risk. Our aim was to investigate the association of CASP8 and CASP9 gene polymorphisms with gastric cancer (GC) susceptibility. METHODS: We undertook a case-control study of 88 GC cases and 480 controls to investigate the association between CASP8 -652 6N ins/del and...

Topics

Aged
Case-Control Studies
Caspase 8
Caspase 9
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Middle Aged
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stomach Neoplasms

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Identifiers

PMID: 21461653
DOI: 10.1007/s10120-011-0045-1

Genes

CASP8
CASP9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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