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Article

Interactions that determine the assembly of a retinoid X receptor/corepressor complex.

Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002

Ghosh Jagadish C, Yang Xiaofang, Zhang Aihua, Lambert Millard H, Li Hui, Xu H Eric, Chen J Don

Abstract excerpt

The retinoid X receptor (RXR) is a key regulator in multiple signaling pathways because it can form either a homodimer with itself or a heterodimer with members of the class I nuclear receptors. The RXR-containing dimers regulate transcription by recruiting coactivators or corepressors to the target promoters. The binding of coactivators to RXR is mediated through a hydrophobic pocket formed in part by the...

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Source

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Identifiers

PMID: 11972046
DOI: 10.1073/pnas.092043399
PMCID: PMC122864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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