Article
Auto-silencing by the retinoid X receptor.
Journal of molecular biology - 20 Nov 1998
Kersten S, Dong D, Lee W y, Reczek P R, Noy N
Abstract excerpt
Gene transcription is often regulated by small ligands, enabling cells to respond to external and metabolic stimuli. Of particular interest are the mechanisms by which hydrophobic hormones modulate the transcriptional activities of proteins of the nuclear receptor superfamily. It was previously shown that, in the absence of ligand, the retinoid X receptor (RXRalpha) forms tetramers with a high affinity and a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
