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Article

Requisite roles of Runx2 and Cbfb in skeletal development.

1 Jan 2003

Abstract excerpt

Each Runx (runt-related gene) protein exerts a fundamental role in different cell lineages. Runx2 is essential for osteoblast differentiation and plays an important role in chondrocyte maturation. Runx2 determines the lineage of osteoblastic cells from multipotent mesenchymal cells, enhances osteoblast differentiation at an early stage, and inhibits osteoblast differentiation at a late stage. In addition, Runx2...

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Identifiers

PMID: 12811622
DOI: 10.1007/s00774-002-0408-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Requisite roles of Runx2 and Cbfb in skeletal development.PMID 12811622Read ↗

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Runx2: A master organizer of gene transcription in developing and maturing osteoblastsSemantic proximity Read ↗

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[Cbfa1/Runx2, an essential transcription factor for the regulation of osteoblast differentiation].Semantic proximity Read ↗

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