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Article

Deletion of Runx2 in condylar chondrocytes disrupts TMJ tissue homeostasis

1 Nov 2018

Abstract excerpt

Runt-related transcription factor-2 (Runx2) is essential for chondrocyte maturation during cartilage development and embryonic mandibular condylar development. The process that chondrocytes, especially a subgroup of hypertrophic chondrocytes (HC), could transform into bone cells in mandibular condyle growth makes chondrocytes crucially important for normal endochondral bone formation. To determine whether Runx2...

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PMID: 30387127
DOI: 10.1002/jcp.26761

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