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Article

Human papillomavirus-16 E7 protein inhibits the DNA interaction of the TATA binding transcription factor.

Journal of cellular biochemistry - 1 Jan 2002

Maldonado Edio, Cabrejos María Eugenia, Banks Lawrence, Allende Jorge E

Abstract excerpt

Previous studies have shown that the HPV-16 E7 protein interacts with TBP. This interaction was found to take place through residues in the carboxy terminal half of E7, mutation of which resulted in weaker transforming activity. In addition, binding of E7 to TBP was found to be increased following protein kinase CK2 (casein kinase II) phosphorylation of E7, and mutation of this CK2 site also reduces E7's...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11968006
DOI: 10.1002/jcb.10172

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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