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Article

Suppression of cellular proliferation by the papillomavirus E2 protein

1 Dec 1995

Abstract excerpt

Carcinogenic progression of a human papillomavirus (HPV)-infected cell is often associated with integration of the viral genome in a manner which results in the loss of expression of the viral regulatory protein E2. One function of E2 is the regulation of expression of the viral oncogenes, E6 and E7. Introduction of the bovine papillomavirus type 1 (BPV-1) E2 transactivator (E2-TA) in HeLa cells, an HPV type 18...

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PMID: 7494290
DOI: 10.1128/jvi.69.12.7791-7799.1995

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Suppression of cellular proliferation by the papillomavirus E2 proteinPMID 7494290Read ↗

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