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Article

Pregnancy status and fetal prion genetics determine PrPSc accumulation in placentomes of scrapie-infected sheep.

Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002

Tuo Wenbin, O'Rourke Katherine I, Zhuang Dongyue, Cheevers William P, Spraker Terry R, Knowles Donald P

Abstract excerpt

Ovine scrapie is a fatal neurodegenerative disorder that may be transmitted through exposure to infected uterine and placental tissues. Susceptibility to scrapie is primarily controlled by polymorphisms in the prion protein (PrP) gene. Scrapie in the U.S. Suffolk breed and in many breeds in Europ...

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Identifiers

PMID: 11959902
DOI: 10.1073/pnas.072071199
PMCID: PMC122945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11959902-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Pregnancy status and fetal prion genetics determine PrPSc accumulation in placentomes of scrapie-infected sheep.PMID 11959902Read ↗

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