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Article

PrP(Sc) accumulation in placentas of ewes exposed to natural scrapie: influence of foetal PrP genotype and effect on ewe-to-lamb transmission.

The Journal of general virology - 1 Oct 2002

Andréoletti Olivier, Lacroux Caroline, Chabert Armelle, Monnereau Laurent, Tabouret Guillaume, Lantier Frédéric, Berthon Patricia, Eychenne Francis, Lafond-Benestad Sylvie, Elsen Jean-Michel, Schelcher François

Abstract excerpt

Placentas from scrapie-affected ewes are known to be infectious. Nevertheless, placenta infectivity in such ewes is not systematic. Maternal transmission to lambs is highly suspected but contamination of the foetus in utero has not been demonstrated. Using ewes from a naturally scrapie-infected flock, it was demonstrated that abnormal prion protein (PrP(Sc)) accumulation in the placenta (i) is controlled by...

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Identifiers

PMID: 12237445
DOI: 10.1099/0022-1317-83-10-2607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PrP(Sc) accumulation in placentas of ewes exposed to natural scrapie: influence of foetal PrP genotype and effect on ewe-to-lamb transmission.PMID 12237445Read ↗

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