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Article

Linkage disequilibrium and association of MAPT H1 in Parkinson disease.

American journal of human genetics - 1 Oct 2004

Skipper Lisa, Wilkes Kristen, Toft Mathias, Baker Matthew, Lincoln Sarah, Hulihan Mary, Ross Owen A, Hutton Mike, Aasly Jan, Farrer Matthew

Abstract excerpt

The MAPT H1 haplotype has been associated with four-repeat (4R) tauopathies, including progressive supranuclear palsy, corticobasal degeneration, and argyrophilic grain disease. More controversial is that the same haplotype has been associated with Parkinson disease (PD). Using H1-specific single-nucleotide polymorphisms, we demonstrate that MAPT H1 is a misnomer and consists of a family of recombining H1...

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Identifiers

PMID: 15297935
DOI: 10.1086/424492
PMCID: PMC1182054

Genes

MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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