Article
CD133 (AC133) expression on AML cells and progenitors.
Cytotherapy - 1 Jan 2001
Vercauteren S M, Sutherland H J
Abstract excerpt
BACKGROUND: AML blasts differ in their functional capability, creating a hierarchy of progenitors. CD133 (AC133) is a newly described transmembrane protein expressed on CD34(+) and CD34(-) normal progenitors. We characterized the prognostic significance of CD133 expression in AML and expression of CD133 on AML progenitors thought to be responsible for maintaining this disease. METHODS: AML cells from 102 patients...
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