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Article

Variable aldehyde dehydrogenase activity and effects on chemosensitivity of primitive human leukemic cells.

Experimental hematology - 1 Mar 2017

Bogen Anja, Buske Christian, Hiddemann Wolfgang, Bohlander Stefan K, Christ Oliver

Abstract excerpt

Aldehyde dehydrogenase (ALDH) activity is an established feature of primitive normal human hematopoietic cells, in which it has been associated with a high expression of the 1A1 isoform of ALDH. High ALDH 1A1 activity has been reported to also characterize cells that propagate malignant populations arising in other tissues, but the regulation and basis of ALDH activity in primary human leukemic cells has not been...

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Identifiers

PMID: 27826122
DOI: 10.1016/j.exphem.2016.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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