Article
CD133 allows elaborated discrimination and quantification of haematopoietic progenitor subsets in human haematopoietic stem cell transplants.
British journal of haematology - 1 Jun 2015
Radtke Stefan, Görgens André, Kordelas Lambros, Schmidt Markus, Kimmig Klaus R, Köninger Angela, Horn Peter A, Giebel Bernd
Abstract excerpt
The success of haematopoietic stem cell (HSC) transplantation largely depends on numbers of transplanted HSCs, which reside in the CD34(+) populations of bone marrow (BM), peripheral blood stem cells (PBSC) and umbilical cord blood (UCB). More specifically HSCs reside in the CD38(low/-) subpopulation, which cannot be objectively discriminated from mature CD34(+) CD38(+) progenitors. Thus, better marker...
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