Article
Expression of CD133 on leukemia-initiating cells in childhood ALL.
Blood - 2 Apr 2009
Cox Charlotte V, Diamanti Paraskevi, Evely Roger S, Kearns Pamela R, Blair Allison
Abstract excerpt
Optimization of therapy for childhood acute lymphoblastic leukemia (ALL) requires a greater understanding of the cells that proliferate to maintain this malignancy because a significant number of cases relapse, resulting from failure to eradicate the disease. Putative ALL stem cells may be resistant to therapy and subsequent relapses may arise from these cells. We investigated expression of CD133, CD19, and CD38...
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