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Article

The hypertrophic heart rat: a new normotensive model of genetic cardiac and cardiomyocyte hypertrophy.

Physiological genomics - 1 Jan 2002

Harrap Stephen B, Danes Vennetia R, Ellis Justine A, Griffiths Cory D, Jones Elizabeth F, Delbridge Leanne M D

Abstract excerpt

We describe a new line of rats with inherited cardiomyocyte and ventricular hypertrophy. From a second-generation cross of spontaneously hypertensive and Fischer 344 rats, we selected for low blood pressure and either high or low echocardiographic left ventricular (LV) mass over four generations to establish the hypertrophic heart rat (HHR) and normal heart rat (NHR) lines, respectively. After 13 generations of...

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Identifiers

PMID: 11948289
DOI: 10.1152/physiolgenomics.00006.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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