Article
Identification and validation of Loci and candidate genes linked to cardiac hypertrophy.
Methods in molecular medicine - 1 Jan 2005
Llamas Bastien, Deschepper Christian F
Abstract excerpt
Left ventricular hypertrophy (LVH) is a complex quantitative trait that has a strong prognostic value for cardiovascular mortality and morbidity. Cardiac mass is determined in part by the influence of genetic loci that are known as quantitative trait loci (QTLs), the localization of which can be performed experimentally in genetic animal crosses. The present chapter outlines standard procedures for the selection...
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