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Article

Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Dec 2001

Iemitsu M, Miyauchi T, Maeda S, Sakai S, Kobayashi T, Fujii N, Miyazaki H, Matsuda M, Yamaguchi I

Abstract excerpt

Pressure overload, such as hypertension, to the heart causes pathological cardiac hypertrophy, whereas chronic exercise causes physiological cardiac hypertrophy, which is defined as athletic heart. There are differences in cardiac properties between these two types of hypertrophy. We investigated whether mRNA expression of various cardiovascular regulating factors differs in rat hearts that are physiologically...

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Identifiers

PMID: 11705790
DOI: 10.1152/ajpregu.2001.281.6.R2029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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