Article
Genetic remodeling and transcriptional remodeling of subtelomeric heterochromatin are different.
Biochemistry - 16 Apr 2002
Venditti Sabrina, Di Stefano Glauco, D'Eletto Manuela, Di Mauro Ernesto
Abstract excerpt
The structure, the extension, and the regulatory functions of telomeric and subtelomeric heterochromatin are not completely understood partly due to the difficulty of separating structural from functional features. We have previously observed that genetic alterations of telomeric heterochromatin components relieve transcriptional silencing. We have developed an analytical system allowing the separate...
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