Article
[Assessment of p53 dependent apoptosis in glia-derived tumors of the brain].
Neurologia i neurochirurgia polska - 1 Jan 2001
Kaczmarczyk R, Słodziński H, Trojanowski T, Polz-Dacewicz M
Abstract excerpt
There are conflicting reports in connection with the association of the p53 tumour suppressor gene mutation with the clinical and histopathological progression of gliomas. Glia-derived neoplasms frequently show mutational changes in the p53 gene which result in enhancement of tumorigenesis. The aim of the paper was an assessment of the frequency of mutations in the exon 8 of this gene. The specimens from 14...
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