[Assessment of p53 dependent apoptosis in glia-derived tumors of the brain].

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Article

[Assessment of p53 dependent apoptosis in glia-derived tumors of the brain].

Neurologia i neurochirurgia polska - 1 Jan 2001

Kaczmarczyk R, Słodziński H, Trojanowski T, Polz-Dacewicz M

Abstract excerpt

There are conflicting reports in connection with the association of the p53 tumour suppressor gene mutation with the clinical and histopathological progression of gliomas. Glia-derived neoplasms frequently show mutational changes in the p53 gene which result in enhancement of tumorigenesis. The aim of the paper was an assessment of the frequency of mutations in the exon 8 of this gene. The specimens from 14...

Topics

Adolescent
Adult
Age Factors
Aged
Apoptosis
Brain Neoplasms
Child
Exons
Female
Genes, p53
Glioma
Humans
Male
Middle Aged
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Sex Factors

Source

Open in PubMed

Identifiers

PMID: 11935677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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